hrp0097p2-244 | Late Breaking | ESPE2023

The impact of weight for length on the assessment of congenital growth hormone deficiency

Henry Rohan , Mamilly Leena , Chaudhari Monika , Pyle- Eilola Amy , Wang Jingcai

It has been established that a random growth hormone (rGH) level can be obtained and is useful within the first 28 days of life for establishing a diagnosis of congenital growth hormone deficiency (cGHD). However, it remains unclear if weight-for-length (WfL), a surrogate for adiposity, impacts these levels, similar to how body mass index in older subjects impacts peak growth hormone levels derived from provocation testing. The objective of this study is to determine the impac...